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The Fall of Man or the Human Fall, also called simply The Fall, is a theological doctrine describing the change of humankind's state from sinlessness to depravity. In Christian tradition, the Fall took place when Adam and Eve partook of the forbidden fruit and were expelled from the Garden of Eden, as recorded in the biblical book of Genesis. This Original Sin is considered the root of all the evil propensities and sins that have tainted their descendants—all human beings—throughout history.

Poliomyelitis, or polio, is a highly contagious viral disease caused by any of three serotypes of poliovirus, with symptoms ranging from a mild, nonparalytic form to one that attacks the central nervous system and can result in temporary or permanent paralysis, and even death. Polio has also been known as infantile paralysis, since it most commonly infects younger children and could cause a lifetime of paralysis. Poliovirus is a form of enterovirus (one that infects the gastrointestinal tract), entering through the mouth, spreading by direct exposure to an infected person.