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Comment by pkiler on April 26th, 2017 at 12:39 am

Each odorant molecule must be small enough to be volatile. No one has described an odor-producing molecule with a molecular weight greater than 294. This appears to be the size limit for a molecule to have sufficient volatility to be detected by the nasal receptors.

I don’t believe this MW of 294 limit to be correct.

If you reference this page:
you can note the MW of 325.364 for this molecule.
A molecule that drove the famous perfume of the 1980’s, Giorgio.

Your information seems to be incorrect, or woefully out of date.
This week, I have been making molecules with MW over 400. And I can smell them.

Fragrantly yours,
Paul Kiler
PK Perfumes

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