Rubella

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Rubella
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ICD-10 B06
ICD-O: {{{ICDO}}}
ICD-9 056
OMIM {{{OMIM}}}
MedlinePlus {{{MedlinePlus}}}
eMedicine emerg/388
DiseasesDB {{{DiseasesDB}}}
Rubella virus
Rubella virus TEM B82-0203 lores.jpg
Virus classification
Group: Group IV ((+)ssRNA)
Family: Togaviridae
Genus: Rubivirus
Species: Rubella virus

Rubella (also known as epidemic roseola, German measles, liberty measles[1] or three-day measles) is a disease caused by the Rubella virus. It is often mild and an attack can pass unnoticed. However, this can make the virus difficult to diagnose. The virus usually enters the body through the nose or throat. The disease can last 1-5 days. Children recover more quickly than adults. Like most viruses living along the respiratory tract, it is passed from person to person by tiny droplets in the air that are breathed out. Rubella can pose a serious risk as it can also be transmitted from a mother to her developing baby through the bloodstream via the placenta. If the mother is infected within the first 20 weeks of pregnancy, the child may be born with congenital rubella syndrome, which includes a range of birth defects. The virus has an incubation period of 2 to 3 weeks during which it becomes established.

The name German measles has nothing to do with Germany. It comes from the Latin germanus, meaning "similar", since rubella and measles share many symptoms.

Symptoms

File:Rubella.JPG
Rubella rash on the abdomen

Symptoms of rubella include:

Children: Low grade fever, swollen glands, joint pain, headache, conjunctivitis, rash

Adults and children:

  • swollen glands or lymph nodes (may persist for up to a week)
  • fever (rarely rises above 38 degrees Celsius [100.4 degrees Fahrenheit])
  • rash (Appears on the face and then spreads to the trunk and limbs. It appears as pink dots under the skin. It appears on the first or third day of the illness but it disappears after a few days with no staining or peeling of the skin)
  • Forchheimer's sign occurs in 20% of cases, and is characterized by small, red papules on the area of the soft palate
  • flaking, dry skin
  • nerves become weak or numb (very rare)

Risks

Rubella can affect anyone of any age and is generally a mild disease. However, rubella can cause congenital rubella syndrome in the fetus of an infected pregnant woman. Usually occurs between 14 - 21 weeks of pregnancy.

Prevention and treatment

Symptoms are usually treated with paracetamol until the disease has run its course. There is no treatment available for congenital rubella.

Fewer cases of rubella have occurred ever since a vaccine became available in 1969, although decreased uptake of the MMR vaccine (e.g. in the UK) is expected to lead to a rise in incidence. In most Western countries, the vast majority of people are vaccinated against rubella as children at 12 to 15 months of age. A second dose is required before age 11. The vaccine may give lifelong protection against rubella. A side-effect of the vaccine can be transient arthritis.

The immunization program has been quite successful with Cuba declaring the disease eradicated in the 1990s and the United States eradicating it in 2005 [1]. Every minister of health in the Americas plans to eliminate the disease by 2010.

The state of Montana requires all brides to be tested for Rubella before a marriage license is issued [2].

Rubella in popular culture

  • Agatha Christie's The Mirror Crack'd from Side to Side features a plot, possibly based on real life, in which a girl is shut in quarantine for a minor illness but climbs out of the window to meet a celebrity. The celebrity is pregnant and unknowingly catches rubella resulting in a child with congenital rubella syndrome. However, as this is the fan's favourite anecdote, when she meets the celebrity years later she tells her the story and the celebrity realises that her baby's syndrome was caused by this fan.
  • In Making Fiends, Vendetta makes a friend named Rubella.
  • The Smoking Popes have a love song called Rubella in which the vocalist professes his love to a particularly itchy love interest.

References
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Commons
Wikimedia Commons has media related to::
  1. Over Here: World War I on the Home Front. Digital History. Retrieved 2006-07-12.

External links

  • Rubella at Wong's Virology, accessed on 24th January 2006.
  • [3] Immunization Safety Review


Exanthema edit
Measles (1st disease) - Scarlet fever (2nd disease) - Rubella (3rd disease)
Duke's disease (4th disease) - Slap cheek (5th disease) - Roseola (6th disease)

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