The fact that in the currently popular taxonomic scheme gorillas and humans are classified as members of the same family, the Hominids, shows just how similar these organisms are physically. If the essence of differentiating humans and gorillas was based solely on comparison of DNA base pairs or anatomical aspects (opposable thumbs, lack of external tails, arrangement of internal organs, blood types, etc.), then one would say these organisms are extraordinarily similar, differing only in degree. While humans may have small front teeth and large molars relative to the gorillas, have bipedalism for posture, a larger brain, and a flattening of the muzzle area of the face, among a few other aspects of physical appearance, these are minor relative to physical differences between say the great apes and the lesser apes.
However, humans are not just physical beings, and the essence of comparison does not have to be limited to DNA base pairs and anatomical aspects. There are also cultural, mental, social, psychological, and spiritual aspects comparisons that can be made, and here the differences are striking. People have complex forms of verbal communication, use symbols in communication unlike any other animal, have complex social organizations, and have complex technologies. Humans practice religions, have diverse systems of governance, and exceptional creativity. Many religions also see humans as endowed with a spiritual body, soul, or eternal spirit, which differentiates them from other animals.